Mitochondrial Degeneration – The Degeneration of Body Main Energy Plants

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Mitochondria are the ‘energy producing plant’ for the cells of our body. More than 200 types of diseases experienced by people are related to mitochondria function problem including common diseases such as Alzheimer’s disease, diabetes, cancer, heart disease, Parkinson disease and stroke.

Mitochondria photo by electron microscopy.
Two mitochondria from mammalian lung tissue. Image credit:

Mitochondria are known as ‘the energy plant’ for cells because it produces adenosine triphosphate (ATP), which is a biological energy supply to do activities. When we are young, mitochondria produce enough ATP for us to keep active. Most cells have 200 to 5000 mitochondria. Cell that has more numbers of mitochondria can produce more energy. Our cells in the body have around 10 million billion of mitochondria, and it makes 10 percent of our body weight.

Mitochondria Dysfunction

Since mitochondria dysfunction was explained in the 1960s, the medical area has increases the understanding of the role of mitochondria in health, disease and aging. Many health problems were eventually related to weakness of mitochondria function. Mitochondria damage also has been accused to be the main contributor of aging process.

Mitochondria Preservation

A research published in the Journal of Clinical Nutrition has found that combination of Alpha Lipoic Acid and Acetyl L-Carnitine can better reduce free radical compared to the use of either substance separately. The combination work in synergy to help avoid mitochondrial damage and regain it function during aging process.

Heart Support

Our heart beats as long as we live and that requires a lot of energy. Since mitochondria produces energy, it is not a surprise that around 50 percent of the volume of heart consist of mitochondria! The more mitochondria the heart has, the more energy it can produce. If the number of mitochondria is low or weakly functioning, it can give adverse effect to the heart. Research has found that the use of Alpha Lipoic Acid will dramatically reduce the oxidative pressure (damage caused by free radicals) in the heart. If the oxidative pressure is lowered, damage of mitochondria also will be lowered. Therefore, the mitochondria can function better with the presence of Alpha Lipoic Acid.

Through aging, you are prone to lose the ability to burn fatty acid (fat) to get energy. Acetyl L-Carnitine is involved in transporting fatty acid into mitochondria for conversion  into energy (Note: Q10 coenzyme is needed to convert fatty acid and glucose into energy). The amount of Acetyl L-Carnitine decreases with the increase of our age and the transport of fatty acid also becomes slow. The heart then becomes deprive of energy from fat. If you take Acetyl L-Carnitine, you will increase the rate of transport and more fatty acid can be brought into mitochondria and used  efficiently to support heart function.

Memory Support

Combination of Alpha Lipoic Acid and Acetyl L-Carnitine helps in increasing memory and thinking performance in adults. There are evidence that mitochondria in brain are very important for memory and thinking function because of it energy generation. Mitochondria dysfunction is related to many type of dementia such as Alzheimer’s and Parkinson. Alpha Lipoic Acid and Acetyl L-Carnitine can cross blood-brain barrier and because of that it benefits the brain.

Anti Aging

A lot of theories on aging already been brought on, the most conspicuous is mitochondria aging theory. This theory suggests that free radicals are formed as by-product of energy production from mitochondria which then causes damage to DNA and the membrane of mitochondria .

Coenzyme Q10 (CoQ10)

CoQ10 plays it role in the function of mitochondria, to complement the action of Alpha Lipoic Acid and Acetyl L-Carnitine:

  • The role of CoQ10 in ATP production is proven. Without CoQ10 mitochondria cannot generate energy.
  • Only Alpha Lipoic Acid can transport fatty acid into mitochondria to be burn as energy by CoQ10 and both work together to increase the function of mitochondria.
  • CoQ10 is a powerful antioxidant. CoQ10 also complement Alpha Lipoic Acid action which also a powerful antioxidant.

Mitochondria Care

Taking supplements that combine Alpha Lipoic Acid (ALA) and Acetyl L-Carnitine added with water soluble CoQ10 will help prevent mitochondria damage and increase the production of energy . Mitochondria care is a good way to preserve our cells, organs and body health as we age.

Everybody can benefit from taking supplements combination of Alpha Lipoic Acid (ALA) and Acetyl L-Carnitine together with water soluble CoQ10. Those in the 40s or younger can experience apparent beneficial effects. The most common reported benefit is increase of energy in daily life and higher mental intelligence.

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